PrP gene expression regulation in sheep : identification of candidate transcription factors that exhibit differential binding to polymorphic variants of the ovine PrP gene promoter

Amino acid variants of PrP<sup>c</sup> particularly at codons 136, 154 & 171 have been linked to scrapie susceptibility, but do not explain all variation in disease phenotype. This study has therefore addressed the hypothesis that unexpected disease occurrence may also be linked to d...

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Bibliographic Details
Main Author: Burgess, Stewart Thomas George
Published: University of Edinburgh 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.642234