The evolution of recombination hotspots and of their relationships with DNA sequences

This thesis attempts to address various aspects of the evolution of recombination hotspots, focusing on the impact of biased gene conversion (BGC) on DNA sequences. My analyses identify thousands of sites in the genome which were active hotspots millions of years ago, illuminate the rate of evolutio...

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Bibliographic Details
Main Author: Tumian, Afidalina
Published: University of Oxford 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.642363