Investigations of age- and plaque-related learning deficits in PDAPP mice and evaluations of anti-amyloidosis strategies on amyloid precursor protein transgenic mice

A cross-sectional and a longitudinal design were employed to address whether PDAPP mice exhibit any plaque-related learning deficit. Firstly, the cross-sectional study indicated that PDAPP mice simultaneously displayed an early (plaque-independent) and age-related learning impairment. Further analys...

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Bibliographic Details
Main Author: Chen, Guiquan
Published: University of Edinburgh 2005
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.642779