Human recombinant Fc constructs : production and anti-osteoclastogenic effects
Staphylococcal protein A (SpA) produced by Staphylococcus aureus, binds Immunoglobulin G (IgG), forming SpA-IgG immune complexes (SIC), at a ratio of 2 SpA molecules to 4 IgG molecules. In vitro, SIC have been found to inhibit human osteoclastogenesis, and reduce proinflammatory cytokine secretion b...
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University of Glasgow
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.643107 |