The role of 5' and 3' sequences in the control of HPRT gene expression

The mammalian HPRT gene is a housekeeping gene. It is expressed constitutively at a low level in all cell types with the exception of the brain where expression is elevated. It has been shown in human brains that HPRT expression is particularly high in the basal ganglia. Total HPRT deficiency in man...

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Bibliographic Details
Main Author: Costello, Patrick Sean
Published: University of Edinburgh 1993
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.645020