Investigation into the chemical modification of active site residues of an aldolase enzyme
It has previously been demonstrated that the biological incorporation and chemical modification of cysteine residues within the active site of the aldolase N-acetylneuraminic acid lyase (NAL) can lead to active chemically modified NAL variants. This thesis reports the exploitation of this joint chem...
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University of Leeds
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.646999 |