A micro-scale study of primary clarification options for the processing of a Fc-fusion protein
This thesis describes the use of ultra scale-down (USD) methods to address the primary recovery challenges posed by the processing of a novel, highly glycosylated Fc-fusion protein expressed in a Chinese Hamster Ovary (CHO) cell line. A feeding strategy coupled with an early cell culture harvesting...
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University College London (University of London)
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.647183 |