Studies of Fv1 binding and restriction

Host restriction factors such as Fv1 in mice and Trim5α in primates block retroviral infection through their interaction with capsids. One major form of Fv1, encoded by the Fv1b allele, restricts only N-tropic MLV (N-MLV) when expressed at the lower endogenous level, but also restricts B-tropic MLV...

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Bibliographic Details
Main Author: Li, H. L. W.
Published: University College London (University of London) 2015
Subjects:
616
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.647323