Determination of the genetic basis of oxytetracycline productivity for Streptomyces rimosus, by the examination of genomic data

Streptomyces rimosus, the industrial strain used in the production of the Type-II polyketide antibiotic oxytetracycline (OTC), has undergone extensive strain improvement over the past 50 years. This has resulted in OTC levels increasing from less than 0.5 g per litre in the original soil isolate to...

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Bibliographic Details
Main Author: MacFadyen, Alison C.
Published: University of Strathclyde 2015
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.647875