Investigation of the Clostridium difficile sortase by gene knockout, X-ray crystallography and biochemical characterisation

The opportunistic pathogen Clostridium difficile is the most common cause of antibiotic-associated diarrhoea, with severity of disease ranging from mild diarrhoea to fulminant pseudomembranous colitis and death. It poses a major burden on healthcare providers, costing millions of pounds each year du...

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Bibliographic Details
Main Author: Chambers, Christopher James
Other Authors: Acharya, K-Ravi
Published: University of Bath 2014
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648944