Manipulation of gene targeting frequency in mammalian cells
With the development of nuclear transfer from somatic cells in several species, gene targeting can now be utilised for the design of more accurate animal models for human diseases and the generation of genetically modified livestock. However, its use is limited by the low frequency of homologous rec...
| Main Author: | |
|---|---|
| Published: |
University of Edinburgh
2000
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.649616 |