The effects of changes in structure of plasmid-encoded β-lactamases on the binding of third-generation cephalosporins

The gene encoding TEM-E2 (<I>bla</I>T-E2), an ESBL identified in an isolate of <I>Klebsiella oxytoca</I> responsible for an outbreak of infection in a neonatal unit in Liverpool in 1982, was sequenced. As cloning from PCR-amplified DNA fragments proved difficult, a new techni...

Full description

Bibliographic Details
Main Author: Du Bois, Stephen Keith
Published: University of Edinburgh 1994
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.649744