Genetic manipulation of fat in transgenic mice
The present dissertation describes the use of a novel system to achieve specific cell ablation in fat tissue. The method is based on the use of <i>E.coli</i> nitroreductase (NTR) enzyme that activates certain nitro compounds into cytotoxic DNA interstrand cross-linking agents. This syste...
| Main Author: | |
|---|---|
| Published: |
University of Edinburgh
2001
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.650832 |