Mechanism of growth inhibition of cAMP analogues on cultured cancer cells

Adenosine 3',5'-cyclic monophosphate (cAMP) analogues have antiproliferative effects on a range of cancer cells including breast, colon and lung. The most potent analogue, described to date, is 8-chloro cAMP but its mechanism of inhibition is poorly understood. The aim of this thesis was t...

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Bibliographic Details
Main Author: Gilbert, Robin Leon
Published: University of Edinburgh 1991
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.651457