Gene targeting in embryonic stem cells and the manipulation of milk composition
Mice carrying mutated β-casein genes were created through gene targeting in embryonic stem cells using a replacement-type vector. β-casein was absent from the milk of homozygous mutant mice, and no mRNA was detectable from the mutant allele. The mutation was compatible with viability, fertility and...
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University of Edinburgh
1994
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.653581 |