De novo methyltransferases, DNA methylation and cancer : a transgenic model

One of the most important controversies in the field of cancer epigenetics is the question of whether aberrant CpG island methylation of tumour suppressor genes can cause cancer or whether such abnormalities of DNA methylation are secondary to the malignant process. We address this question by prosp...

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Bibliographic Details
Main Author: Latham, Tom
Published: University of Edinburgh 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.653693