The effects of nonsteroidal anti-inflammatory drugs on nuclear factor-kappaB and Beta-catenin signaling in colorectal cancer cells
The first research strand in this thesis was to determine whether non-aspirin NSAIDs induce apoptosis of colorectal cancer cells via modulation of the NF-κB pathway and to elucidate the upstream mechanisms involved. Experimental evidence presented here shows that sulindac, sulindac sulfone and indom...
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University of Edinburgh
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.654058 |