Understanding the role of Merkel cell polyomavirus oncoproteins in the cellular transformation of mammalian Merkel cells

Merkel cell carcinoma (MCC) is a highly aggressive skin cancer of neuroendocrine origin with a high propensity for metastasis through the dermal lymphatic system. In 2008, Merkel cell polyomavirus (MCPyV) was discovered monoclonally integrated within the host genome of more than 80% of MCC tumours....

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Bibliographic Details
Main Author: Knight, Laura M.
Other Authors: Whitehouse, Adrian
Published: University of Leeds 2014
Subjects:
570
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.655247