Realising lead-oriented synthesis

The concept of lead-oriented synthesis (LOS) seeks to address to the paucity of diverse compounds with appropriate properties for biological screening. This thesis focuses on the preparation of diverse scaffolds, which, following decoration, may provide access to lead-like compounds. Key polyfunctio...

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Bibliographic Details
Main Author: Foley, Daniel Jason
Other Authors: Marsden, Stephen P. ; Nelson, Adam S.
Published: University of Leeds 2015
Subjects:
540
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.655264