Investigating the role of the CCL2/CCR2 axis in monocytes and its modulation by extracellular nucleotides
The chemokine CCL2 activates its cognate receptor CCR2 to orchestrate monocyte trafficking towards infected, inflamed, and injured tissues during immune responses and the development of inflammatory disease. However, despite research into this area being plentiful, CCR2 antagonists have lacked clini...
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University of East Anglia
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656142 |