Synthesising nucleoside analogues for imaging proliferation in cancer and other biomedical applications
Rapidly proliferating cells, such as cancerous cells, show increased reliance on deoxyribonucleic acid (DNA) salvage pathways for producing nucleotides required for DNA synthesis. As such targeting these salvage pathways using radiolabelled nucleosides can provide a means of imaging the extent of pr...
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Imperial College London
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656366 |