Investigating the mechanisms of influenza polymerase host adaptation

An avian virus can become adapted to humans by mutating or recombining with currently circulating human viruses. These viruses have the potential to cause pandemics in an immunologically naïve human population. Host restriction involves multiple determinants, however, influenza polymerase is consid...

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Bibliographic Details
Main Author: Cauldwell, Anna
Other Authors: Barclay, Wendy
Published: Imperial College London 2014
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656618