Electrophysiological investigation of the mechanism of action of xenon on ion-channels and determination of the neuroprotective potential of xenon in an in vivo model of traumatic brain injury
Xenon is a general anaesthetic gas with neuroprotective properties. Inhibition of the N-methyl-D-aspartate (NMDA) receptor glycine co-agonist site has been shown to mediate xenon neuroprotection against ischemic injury in vitro. Site-directed mutagenesis was used to produce point mutations in the Gl...
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Imperial College London
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656627 |