The role of complex II of the mitochondrial respiratory chain in cell death induction

Complex II of the respiratory chain (RC) recently emerged as a prominent regulator of cell death. In both cancer as well as neurodegenerative diseases, mutations in its subunits have been found along with other genetic alterations indirectly affecting this complex. Moreover, anticancer compounds wer...

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Bibliographic Details
Main Author: Hwang, Ming
Other Authors: Grimm, Stefan
Published: Imperial College London 2014
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656682