Tumour-specific regulation of apoptin by protein kinase C

Apoptin, the VP3 protein derived from chicken anaemia virus (CAV), induces tumour cell-specific apoptosis and therefore represents a potential anti-cancer therapeutic agent of the future. In human tumour cells, but not in normal cells, Apoptin is phosphorylated and subsequently translocates to the n...

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Bibliographic Details
Main Author: Bullenkamp, Jessica Isabell
Other Authors: Tavassoli, Mahvash; Ng, Tony Tsz-cheong
Published: King's College London (University of London) 2014
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656938