Roles for Mph1 kinase in the spindle checkpoint and chromosome segregation
The spindle checkpoint monitors the metaphase-to-anaphase transition to ensure accurate segregation of sister chromatids during mitosis to prevent aneuploidy. Mph1, the fission yeast homologue of Mps1 is one of the kinases involved in the spindle checkpoint. Deletion of Mph1 results in cells with a...
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University of Edinburgh
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.657827 |