Gene targeting studies at the mouse prion protein locus
The prion protein (PrP<SUP>c</SUP>) is a normal host-encoded glycoprotein which accumulates as a disease specific protease-resistant isoform (PrP<SUP>sc</SUP>) in the brains of infected hosts. In a number of species PrP polymorphisms and germline mutations are associated with...
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University of Edinburgh
1997
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.657967 |