RNA-mediated mechanisms of human ageing

Human ageing is a complex deterioration in overall tissue function and is the major risk factor for chronic disease. Understanding the fine-tuning of gene expression may be pivotal in this process. In this thesis, I describe gene expression and the regulation of alternative splicing as a novel mecha...

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Bibliographic Details
Main Author: Holly, Alice Carole
Published: Exeter and Plymouth Peninsula Medical School 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.658032