Regulatory T cells in haematopoietic stem cell transplantation

Graft-versus-host disease (GvHD) remains the main complication associated with haematopoietic stem cell transplantation (HSCT). GvHD is caused by allo-reactive donor T cells mounting an attack against specific target tissues. CD4+CD25HiFoxp3+ regulatory T cells have been shown to modulate GvHD in vi...

Full description

Bibliographic Details
Main Author: Mavin, Emily
Published: University of Newcastle upon Tyne 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.658351