Functional analysis of motor neuron disease-associated mutations in TAR DNA-binding protein 43 and cytoplasmic dynein heavy chain 1

Amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy with lower extremity predominance (SMA-LED) are two forms of motor neuron diseases at the opposite ends of the age spectrum, with ALS being mainly an adult-onset progressive and fatal neurodegenerative disease, and SMA-LED being a child...

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Bibliographic Details
Main Author: Barri, Muruj Asaad
Published: University of Sussex 2015
Subjects:
572
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.658955