Investigations into the specificity and mechanism of action of the attenuated adenovirus dl1520 with particular reference to head and neck cancer

This thesis is concerned with investigating the selectivity; mechanisms of action and optimisation of delivery of the novel anti-cancer agent dl1520 (previously called Onyx-015). dl1520 is an attenuated adenovirus which has been genetically modified to have a selective cytolytic action against tumou...

Full description

Bibliographic Details
Main Author: Morley, Stephen E.
Published: University of Edinburgh 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.659769