Investigations into the specificity and mechanism of action of the attenuated adenovirus dl1520 with particular reference to head and neck cancer
This thesis is concerned with investigating the selectivity; mechanisms of action and optimisation of delivery of the novel anti-cancer agent dl1520 (previously called Onyx-015). dl1520 is an attenuated adenovirus which has been genetically modified to have a selective cytolytic action against tumou...
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University of Edinburgh
2004
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.659769 |