The extent of genotype specific humoral immunity produced on infection with hepatitis C virus : relevance for serological screening and diagnosis

Sequence variation in the antigenic determinants in core, NS3, NS4A/B and NS5A/B proteins, may produce genotype-specific antibodies which do not cross-react with the antigens used in current screening assays for detection of antibody to HCV. The extent of type-specific and type-common components of...

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Bibliographic Details
Main Author: Neville, Judith Anne
Published: University of Edinburgh 2003
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.659936