p53 death pathways in cisplatin-damaged primary murine colonocytes and a possible role for hedgehog developmental genes in colon carcinogenesis

Much of the information on carcinogenesis in the intestine derives from studies based on the small intestine, yet the majority of the mutations leading to cancer occur in the large intestine. To overcome some of these issues, the use of a large bowel model and in particular the primary murine colono...

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Bibliographic Details
Main Author: Oniscu, Anca
Published: University of Edinburgh 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.660210