An evaluation of whole gut lavage fluid for the detection of colorectal cancer using molecular techniques
DNA was extracted from WGLF obtained pre-operatively from 40 patients undergoing cancer resections. This was analyzed for mutations in 4 genes commonly altered in CRC. Analysis consisted of a PCR/restriction enzyme enrichment strategy for Ki-ras and p53 mutations, while APC and Transforming growth f...
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University of Edinburgh
2000
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.660707 |