The NuRD complex has a role in the specification of DNA methylation patterns in pluripotent cells
The NuRD (Nucleosome Remodelling and Deacetylation) complex is a highly conserved and abundant transcriptional repression complex. Embryonic Stem (ES) cells lacking a central structural component of the complex, Mbd3, proliferate slowly and are unable to differentiate in the absence of LIF. We show...
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University of Edinburgh
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.660715 |