Adapting yeast to the study of higher eukaryotes : 'humanisation' of histone H4

Seven of the eight differences between the yeast and human histone H4 amino acid sequences fall within the globular histone fold domain. The other is a conservative isoleucine to value substitution in the more flexible N-terminal tail (I21V). A yeast mutant expressing a form of histone H4 with the s...

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Bibliographic Details
Main Author: Rushton, Sally
Published: University of Edinburgh 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.661463