Genetic control of apoptosis and tumourigenesis in murine models of intestinal neoplasia

Perturbations to the normal apoptotic response would be predicted to impact upon longer term survival as determined through the microcolony assay. I therefore examine clonogenic survival using this approach in Msh2, Mlh-1 and p53 null mice. Despite being necessary for apoptosis for all cytotoxic age...

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Bibliographic Details
Main Author: Sansom, Owen James
Published: University of Edinburgh 2002
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.661579