The development of genetic models to understand the role of the Wilms' tumour suppressor gene, WT1
This thesis describes the use of gene targeting in embryonic stem cells, to develop two different genetic systems to facilitate the investigation of WT1 function. Firstly, using the <i>Cre/LoxP</i> system a conditional null allele for WT1 was generated by targeting the WT1 locus in embry...
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University of Edinburgh
2003
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.662323 |