Macrophage chemotaxis to apoptotic cells

The CD14 knockout mouse (CD14-/-) was observed to have increased numbers of free apoptotic cells in the thymus. It was hypothesised that this was due to a defect in macrophage clearance of dying cells. <i>In vitro </i>assays revealed that macrophages from the CD14-/- mouse had a partial...

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Bibliographic Details
Main Author: Truman, Lucy
Published: University of Edinburgh 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.663059