IFNγ induced apoptosis in the murine hepatocyte

Specifically we set out to identify the upstream caspases that were activated by IFNγ and the role of the mitochondria in apoptosis. We selected an <i>in vitro </i>primary murine hepatocytes system to investigate this pathway. Despite experimental difficulties and questions about the rel...

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Bibliographic Details
Main Author: Tura, Benjamin James
Published: University of Edinburgh 2005
Subjects:
611
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.663092