Pharmacological characterisation of novel furoxans and furoxan-aspirin hybrid drugs in blood vessels, inflammatory cells and platelets

A novel range of hybrid drugs in which a furoxan nitric oxide (NO)-donating moiety is joined by ester linkage to the aspirin molecule were developed in the hope that the cytoprotective actions of drug-derived NO would overcome the gastric side-effects of aspirin. In addition, the presence of the NO...

Full description

Bibliographic Details
Main Author: Turnbull, Catriona M.
Published: University of Edinburgh 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.663095