Examination of the role of the Wilms' tumour suppressor gene (Wt1) in mouse development and neoplasia using a homozygous Denys-Drash syndrome mutation
Denys-Drash syndrome, which is characterised by genitourinary abnormalities, a type of progressive nephropathy known as mesangial sclerosis and the development of Wilms' tumours, results from mutations in the zinc finger-coding region of one copy of the <i>WT1</i> gene. Murine ES ce...
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University of Edinburgh
2001
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.663328 |