Malignant hypertension in the transgenic Ren-2 rat

The transgenic rat line TGR(mREN2)27 has been previously shown to develop severe hypertension as a consequence of over-expression of the mouse Ren-2 renin gene. The heterozygote cross HanRen2/Edin - was found to develop malignant phase hypertension within a relatively narrow age range. Seventy-three...

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Bibliographic Details
Main Author: Whitworth, Caroline Elizabeth
Published: University of Edinburgh 1995
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.663737