HPRT deficiency in cells and mice
The hypoxanthine guanine phosphoribosyltransferase (HPRT) gene is a housekeeping gene, located on the X chromosome in both human and mouse. In humans, HPRT deficiency causes Lesch-Nyhan syndrome which is characterised by behavioural alterations, including self-injurious behaviour and mental retardat...
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University of Edinburgh
1993
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.664055 |