CAG.CTG trinucleotide repeat instability in the E.coli chromosome

In order to identify the molecular basis of genetic instability, a polymerization-independent strategy is developed to generate expanded repeat arrays. The repeat tracts are integrated in the 5’end of <i>lacZ</i> gene in the <i>Escherichia coli</i> chromosome. Using this mode...

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Bibliographic Details
Main Author: Zahra, Rabaab
Published: University of Edinburgh 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.664197