The modification of biotin analogues to function as multipurpose labelling tools

This project has focused on establishing a specific multipurpose labelling system via the modification of D-( + )-biotin in use with (strept)avidin proteins for purification and isolation. Two biotin analogues; 2-azidobiotin and 2-propargylbiotin, have been synthesised, introducing an alkyne and azi...

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Bibliographic Details
Main Author: Sehmi, Inderpal Kaur
Published: University of Nottingham 2014
Subjects:
540
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.664312