The assay of nitroreductases with CB1954 and immobilisation onto gold surfaces

Directed enzyme prodrug therapies (DEPT) are currently being clinically trialled, the aim being to localise cytotoxic compounds at cancer sites; enzymes are either expressed or delivered to solid tumours so that non-toxic prodrugs are activated to cytotoxic derivatives exclusively at cancer cells. N...

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Bibliographic Details
Main Author: Cude, Matt
Published: Bangor University 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.664601