Investigation of the underlying mechanism of x-linked adrenoleukodystrophy in a Saccharomyces cerevisiae model
X-linked Adrenoleukodystrophy is the most common peroxisomal disorder. This neurodegenerative disorder is caused by mutations within the ABCD1 gene which encodes a half-ABC transporter protein that resides in the peroxisomal membrane. Patients suffering from X-ALD fail to transport very long chain f...
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University of Sheffield
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.665016 |