Characterisation of regulatory regions of the PRNP gene and their effect on susceptibility to sporadic and variant Creutzfeldt-Jakob Disease
Based on analysis of PrP gene regulatory regions in other species, 4.8 Kb of human genomic sequence containing 1.5Kb of upstream sequence the first exon and 3.1Kb of intron was cloned from a human genomic lambda library into a CAT reporter gene. Transient transfections in human neuroblastoma cells o...
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University of Edinburgh
2001
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.666128 |