The sensitisation of TRPV1 mediated responses by prostaglandin and bradykinin and the signalling pathways involved
TRPV1 ion channels have crucial roles in inflammatory hyperalgesia as TRPV1-/- mice show reduced thermal hyperalgesia response in response to tissue inflammation. The activity of TRPV1 is upregulated in the case of inflammation due to the release of different inflammatory mediators which can modulat...
| Main Author: | |
|---|---|
| Other Authors: | |
| Published: |
University of Leicester
2015
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.668359 |